A Parasitic Puzzle: Exploring the genomic secrets of Australian ticks

A Parasitic Puzzle: Exploring the genomic secrets of Australian ticks

In the field of genomics, researchers like Dr Amanda Duarte Barbosa are driven by an insatiable curiosity to unravel the mysteries held within the DNA of various organisms. A Senior Lecturer and Researcher at the Vector and Waterborne Pathogens Research Group, Murdoch University, WA, Amanda specialises in the molecular epidemiology of vector-borne pathogens that affect the animal-human-ecosystem interface, and it’s the enigmatic tick that has captured her attention.

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Five Women in Science - Associate Professor Sarah Auburn

Five Women in Science - Associate Professor Sarah Auburn

Associate Professor Sarah Auburn is a molecular biologist, whose passion is using genetics/genomics to learn about the biology and the epidemiology of pathogens and their hosts. A/Prof Auburn's current research program incorporates molecular biology, population genomics and software development to generate laboratory and analytical tools for molecular surveillance of P. vivax towards elimination of this species.

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Five Women in Science - Associate Professor Tu Nguyen-Dumont

Five Women in Science - Associate Professor Tu Nguyen-Dumont

Associate Professor Tu Nguyen-Dumont from Monash University. Associate Professor Tu Nguyen-Dumont serves as the genomics and bioinformatics lead in several multidisciplinary teams dedicated to exploring and defining genomic variations associated with cancer risk, cancer development, recurrence, and response to treatment.

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Five Women in Science - Dr Lisa Stinson

Five Women in Science - Dr Lisa Stinson

Dr Lisa Stinson is from The University of Western Australia. Dr Stinson’s work aims to understand infant microbiome assembly in relation to the breast milk composition and infant feeding practices, and to identify mechanisms through which breast milk composition and infant microbial colonization shape life-long health.

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AGRF Annual Report FY2022-23 is out!

We are so pleased to share our Annual Report for Financial Year 2022-23. You can view and download a copy of the report by clicking on the image.

“At AGRF, we believe that genomics has the power to transform primary industries and clinical genomics while driving innovation and contributing to valuable research in emerging fields such as single cell and spatial genomics. We are committed to continuing our work in these areas and collaborating with our partners to achieve shared goals for a healthier, more sustainable planet.” - Professor Simon Foote (Chairman).

With over 25 years of delivering exceptional genomic services to Australia and beyond, we are excited to share the stories from the past year with you.

Many thanks to all who have contributed to this report. The stories inside showcase the outstanding work being done by our staff, clients and partners and we are thrilled to share them with you here.

“By working together with our partners, we leverage our collective expertise and resources to achieve shared goals and drive innovation in genomics research and development.” - Joe Baini (Chief Executive Officer).

Click on the image to start reading or download here.

If you wish to receive a hard copy of the Annual Report, please email Louise.Hockham@agrf.org.au with your current mailing address and we will send one out to you. 

We would like to take this opportunity to thank all our clients, partners, and staff for their ongoing support and we look forward to working with you in 2024. 

How Genomics Is Making Phage Therapy a Reality

How Genomics Is Making Phage Therapy a Reality

Bacteria have long been a challenging adversary in the world of medicine. Antibiotics have been a primary treatment for bacterial infections, but their overuse has led to the emergence of antibiotic-resistant (AMR) bacteria, causing a significant health threat (refer health economics report commissioned by Iredell, Lin et al, Phage Australia). A promising revival of phage therapy is set to combat AMR infections more effectively and with fewer side effects than antibiotics.

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Beyond The Reference Genome: How pangenomics is changing the game

Beyond The Reference Genome: How pangenomics is changing the game

Reference genomes have long been the backbone of genomic research. These 'one-size-fits-all' representations are typically constructed from sequencing projects that use just a single representative. While there is no doubt that they have been invaluable, they fall short in capturing the full genetic diversity within a species - who’s to say that the one individual chosen to be sequenced has the full gamut of every piece of information in their genome?

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Journey Through the Stars: Insights from NASA's STAR program.

Journey Through the Stars: Insights from NASA's STAR program.

As World Space Week comes to a close, join us in following the stellar journey of our own Kirk Jensen, as he shares his remarkable experience within the NASA STAR program. The STAR course was put together by NASA to offer intense training in fundamental space biology and in how to conceive and conduct biological/biomedical research projects in space.

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Off-world Living Through Plants for Space (P4S)

Off-world Living Through Plants for Space (P4S)

Imagine being stranded on a desert island in the middle of nowhere, having to survive off whatever you can find. Now picture an extreme level where there are no plants, animals, oxygen, and very little sunlight. Well, this daunting scenario is what space-faring humans will face as we start to settle on the moon, Mars, and beyond.

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ZERO: A hopeful future for children with cancer

ZERO: A hopeful future for children with cancer

In Australia, more than 1,000 children and adolescents are diagnosed with cancer every year. While the overall survival rate for childhood cancer is now over 80%, for some types of cancer the rate is much lower. Every week, three young lives are lost to cancer – more than to any other disease.

In 2021, AGRF joined a unique collaboration aiming to improve these statistics, becoming a key partner in the Zero Childhood Cancer Program (ZERO), Australia’s first national precision medicine program for children with cancer..

Learn how AGRF are helping to make a difference.

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AGRF Appoints Joe Baini as New CEO

MR JOE BAINI, CHIEF EXECUTIVE OFFICER, AGRF

On behalf of the AGRF Board and AGRF staff, we are pleased to announce the appointment of Joe Baini as Chief Executive Officer of the Australian Genome Research Facility.

AGRF Board Chairman, Emeritus Professor Simon Foote says, “On behalf of the AGRF Board, I am pleased to announce that Mr Joe Baini has been appointed as Chief Executive Officer at AGRF. Joe has immense experience in leading technology-focused companies. He has been interim CEO of AGRF for the past few months and the board has been impressed with his performance. We look forward to accompanying Joe Baini, the executive team and all of AGRF on our voyage over the next few years.”

Mr Baini says, “I am honoured to be joining AGRF, our national, pre-eminent genomics organisation.  Our team members across the country have proven themselves to be high performing and focused on delivering exceptional service to clients. We aim to continue serving the Australian genomics research community and our clinical and commercial partners with the reliability they have come to know. We are additionally excited to support our partners in their efforts to develop real world innovations.”

Mr Baini has more than three decades of experience holding senior management positions in large-scale biotechnology and pharmaceutical companies. With skills in strategic and market development, he has achieved success as the CEO of multinational, ASX-listed organisations since 2011.

Previously Mr Baini led the establishment of Gilead Sciences across Asia Pacific and built the fledgling organisation into a significant player in the pharmaceutical sphere. Prior to joining AGRF as Interim CEO earlier this year, Mr Baini worked as CEO of Immuron and PresSura Neuro and has been Principal of Exec Factor since 2008. He has also served on the board of both ASX-listed and privately held pharmaceutical and biotechnology sector companies for ten years.  In addition, he held a guest lecturer position for several years in the Masters of Biotechnology at the University of Melbourne, specialising in commercialisation of new technologies, and brings his background and experience of executive coaching and business mentoring to his new role at AGRF.

Please join us in officially welcoming Joe Baini to the role of CEO. We look forward to 2022 and beyond, and we wish Joe every success.

MEDIA CONTACT
Desley Pitcher
Sales & Marketing Manager
Email: Desley.Pitcher@agrf.org.au
Phone: 0407 395 291

Children’s Cancer Institute Partners with AGRF to Expand the Zero Childhood Cancer Program

ZCC Email banner.jpg

Exciting news this week for AGRF, as we sign an agreement with Children’s Cancer Institute to deliver rapid, high-quality, multi-omics sequencing data to support the Zero Childhood Cancer Program and its partner network in the growing number of sequencing-centric research projects. 

To further evaluate the effectiveness of a comprehensive, multi-faceted molecular approach to paediatric precision medicine, the Zero Childhood Cancer Program will be expanded to include all children and young adults diagnosed with cancer in Australia over the next few years, irrespective of cancer type, risk and stage. Their initial aim is to undertake whole genome sequencing, whole transcriptome sequencing and array-based methylation profiling of more than 10,000 children with cancer. In addition, Children’s Cancer Institute will be launching new population-scale sub studies to further investigate paediatric cancer risk. Over the next five years, patient samples will undergo comprehensive genomic profiling to identify molecular signatures and actionable targets to improve their health outcomes.

Vanessa Tyrrell, Program Leader of ZERO at Children’s Cancer Institute said, “Today, we have over 500 children and young people enrolled on ZERO. As we prepare to expand ZERO to one day give every child diagnosed with cancer the very best chance of survival, we’re excited to partner with AGRF to make this happen. Together, we will strive for a future where all children have the best chance of living their best lives.”

And AGRF’s CEO, Dr Kirby Siemering, said, “At AGRF, we are extremely proud to contribute our technology platforms and expertise in genomics to this incredible project. Working together with the talented team at Children’s Cancer Institute and ZERO partners, we aim to make a meaningful impact on the lives of children living with cancer”.

Led in partnership by Children’s Cancer Institute and Kids Cancer Centre at Sydney Children’s Hospital (Randwick), Zero Childhood Cancer brings together all major Australian clinical and research centres working in childhood cancer, as well as international collaborators.

Announcing the PacBio ANZ HiFi SMRT Grant Winner!

Announcing the PacBio ANZ HiFi SMRT Grant Winner!

We are delighted to announce that Professor Glenn King has been named the recipient of the 2020 PacBio ANZ HiFi SMRT Grant! Prof. King received the grant for his project ‘Deadly Genes: Exploring the Genome of the lethal Australian Box Jellyfish,’ and he plans to use HiFi sequencing in an integrated multi-omics investigation into venom of the Australian box jellyfish Chironex fleckeri.

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